| Methods |
From 12/1975 to 6/1976.
Randomised.
Unknown allocation concealment. Not double blind.
30 excluded from the analysis.
Non intention to treat. |
| Participants |
Any type of stroke: ischaemic, hemorrhagic, carotid and vertebrobasilar stroke.
TIA and SAH excluded.
93 cases in the final analysis + 30 excluded from the analysis.
F = 43, M = 50.
Mean age 67.6 years.
Any severity considered.
Time entry window: 24 hours. |
| Interventions |
50 g glycerol in 500 ml saline i.v. over 2 hours + 16 mg dexamethasone i.m. for 7 days. |
| Outcomes |
Mortality at 7, 30 days. Neurological evaluation, coma and disability status scale at 7 and 30 days. |
| Notes |
Steroids were administered in treatment and in control group.
24 patients out of 93 considered had no CT scan. 30 randomised were excluded from the analyses: 7 had a SAH; 14 in glycerol + dexamethasone group and 9 in dexamethasone group discontinued the treatment. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
