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. 2020 Feb 19;13:1561–1568. doi: 10.2147/OTT.S235349

Table 4.

Toxicity Profile

Toxicity Total No.(%) I + II No.(%) III+ IV No.(%)
Leukopenia 22(69) 16(50) 6(19)
Febrile neutropenia 9(28) 6(19) 3(9)
Thrombocytopenia 4(12) 3(9) 1(3)
Anemia 19(59) 17(53) 2(6)
Anorexia 16(50) 14(44) 2(6)
Nausea/vomiting 14(44) 13(41) 1(3)
Diarrhea 3(9) 3(9) 0(0)
Hypertension 8(25) 6(19) 2(6)
Fatigue 12(38) 12(38) 0(0)
Hand-foot skin reaction 2(6) 2(6) 0(0)
Triglyceride elevation 8(25) 8(25) 0(0)
Proteinuria 7(22) 7(22) 0(0)
ALT elevation 9(28) 9(28) 0(0)
AST elevation 8(25) 8(25) 0(0)
Hypothyroidism 5(16) 5(16) 0(0)