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. Author manuscript; available in PMC: 2020 Feb 24.
Published in final edited form as: Colloids Surf B Biointerfaces. 2014 Jun 11;121:141–149. doi: 10.1016/j.colsurfb.2014.06.011

Fig. 1.

Fig. 1.

A schematic illustration of immunocerasome formation. Hydrolyzed and partially polymerized cerasome-forming lipids (CFL) in acidic ethanol, cholesterol in acidic ethanol, NBD-DPPE in the mixture of ethanol and chloroform, and MAL-DSPE-PEG in chloroform were mixed and injected into PBS, creating organic-inorganic liposomal cerasomes. The polysiloxane networks formed on the surfaces of nanovesicles provide morphological stability. The maleimide-containing cerasomes were readily conjugated with thiolated anti-EGFR mAbs via maleimide-thiol coupling, forming immunocerasomes.