Table IV.
Exposure | Effects |
---|---|
Prenatal very high doses of alcohol | 6-10% of developing foetus have risk of FAS61 |
Alcohol during pregnancy | Adversely affect mother and foetus; women consume excess alcohol are at risk for a child with FAS62 |
Tobacco and smoking | Adverse effect on ovarian function and reversible effects on implantation and ongoing pregnancy. Modify fertility affecting uterine-fallopian tube functions. Miscarriage due to effects of nicotine, Cd and PAHs on trophoblast65 |
Female smoking | Elevates TTP while links with male smoking are ambiguous66 |
Prenatal tobacco smoking | Toxic effects of prenatal tobacco smoking on foetal growth and infant weight67 |
ETS exposure during pregnancy | Risk of SGA and LBW among neonates68 |
Snuff uses during pregnancy | Reduced birth weight 39 g in snuff users and risk of preterm delivery and preeclampsia69 |
Snuff uses during early pregnancy | Risks of SGA births70 |
Smokeless tobacco use in pregnancy | 3-fold increased risk of stillbirth and 2-3 fold risk of LBW71 |
Prenatal smokeless tobacco use | Birth weight reduced 78 g while no association with PTB, hypertension or placental abruption of smokeless tobacco users72 |
Betel quid chewing during pregnancy | Adverse birth outcomes were five times higher73 |
Maternal areca nut chewing during pregnancy | Associated with birth weight loss, birth length reduction. Enhanced risk of LBW with simultaneous use of betel quid, cigarette and alcohol74 |
FAS, foetal alcoholic syndrome; TTP, time to pregnancy; ETS, environmental tobacco smoke; PAHs, polycyclic aromatic hydrocarbons