FIG. 6.

Antioxidant administration strategies for overcoming COC oxidative stress. Several approaches have been studied in humans. Different antioxidants have been administrated orally, in vivo, or after COC collection, in vitro. While different outcomes were evaluated, distinct time frames of administration, concentrations, patient groups, and in vitro conditions make it difficult to find comparable results. In parentheses are the referenced studies for the administration of each substance. Color images are available online.