Table 3.
Variables | GWG (continuous) not adjusting for GA | GWG (continuous) adjusting for GA | GWG below IOM guidelines (<0.35 kg/week) adjusting for GA | GWG less than the third centile of INTERGROWTH‐21st standards not adjusting for GA | GWG <50th centile of INTERGROWTH‐21st standards not adjusting for GA |
---|---|---|---|---|---|
Adolescent | |||||
Yes | −0.004 [−0.08, 0.07] | −0.01 [−0.09, 0.08] | 1.4 [0.9, 2.4] | 0.8 [0.5, 1.4] | 1.0 [0.5, 2.0] |
No | Ref | Ref | Ref | Ref | Ref |
Education | |||||
Any formal education | 0.06 [−0.02, 0.14] | 0.06 [−0.02, 0.14] | 0.9 [0.5, 1.5] | 0.5 [0.3, 0.9]* | 1.1 [0.6, 1.9] |
No education | Ref | Ref | Ref | Ref | Ref |
Principal occupation | |||||
Housewife | −0.06 [−0.15, 0.04] | −0.05 [−0.15, 0.04] | 1.4 [0.9, 2.1] | 1.0 [0.64, 1.57] | 1.0 [0.7, 1.7] |
Nonhousewife | Ref | Ref | Ref | Ref | Ref |
Number of pregnancies | −0.009 [−0.02, 0.002] | −0.009 [−0.02, 0.001] | 1.04 [0.97, 1.12] | 1.1 [0.97, 1.16] | 1.11 [1.03, 1.20]* |
Number of living children | −0.0068[−0.02, 0.01] | −0.009 [−0.02, 0.006] | 1.02 [0.94, 1.11] | 1.1 [0.98, 1.20] | 1.0 [0.9, 1.1] |
Height | 0.004 [−0.001,0.01] | 0.004 [−0.001, 0.01] | 0.96 [0.92, 0.98]* | 0.98 [0.95, 1.02] | 0.94 [0.91, 0.98]* |
Household livestock index | |||||
Above the median | 0.003 [−0.05, 0.06] | 0.001 [−0.06, 0.06] | 1.0 [0.7, 1.4] | 0.8 [0.6, 1.2] | 1.1 [0.8, 1.6] |
At or below the median | Ref | Ref | Ref | Ref | Ref |
Housing quality index | |||||
Above the median | −0.02 [−0.10, 0.06] | −0.02 [−0.10, 0.06] | 1.1 [0.7, 1.6] | 1.1 [0.8, 1.6] | 1.1 [0.6, 1.8] |
At or below the median | Ref | Ref | Ref | Ref | Ref |
Household asset index | |||||
Above the median | −0.02 [−0.08, 0.03] | −0.02 [−0.07, 0.04] | 1.1 [0.8, 1.5] | 1.1 [0.7, 1.7] | 1.2 [0.8, 1.8] |
At or below the median | Ref | Ref | Ref | Ref | Ref |
Reported food intake | |||||
Increased | 0.004 [−0.10, 0.11] | 0.01 [−0.1, 0.12] | 0.9 [0.5, 1.6] | 1.1 [0.6, 2.2] | 1.0 [0.5, 2.0] |
Decreased | −0.005 [−0.09, 0.08] | −0.004 [−0.09, 0.08] | 0.8 [0.4, 1.4] | 1.3 [0.7, 2.4] | 0.9 [0.4, 1.8] |
No change | Ref | Ref | Ref | Ref | Ref |
Number of meals | |||||
Increased | −0.03 [−0.14, 0.08] | −0.03 [−0.13, 0.08] | 1.1 [0.5, 1.9] | 1.2 [0.7, 2.1] | 1.1 [0.5, 2.4] |
Decreased | −0.02 [−0.10, 0.05] | −0.02 [−0.09, 0.05] | 0.8 [0.5, 1.4] | 1.2 [0.8, 2.0] | 1.1 [0.6, 1.9] |
No change | Ref | Ref | Ref | Ref | Ref |
Levels of household food insecurity | |||||
Food secure | −0.06 [−0.17, 0.04] | −0.07 [−0.18, 0.04] | 1.8 [1.0, 3.4]* | 0.20 [0.65, 2.28] | 0.51 [0.84, 3.33] |
Mildly food insecure | −0.03 [−0.15, 0.09] | −0.04 [−0.16, 0.09] | 1.7 [0.8, 3.4] | 0.10 [0.50, 2.60] | 0.15 [0.49, 2.74] |
Moderately food insecure | −0.04 [−0.17, 0.09] | −0.04 [−0.17, 0.09] | 1.4 [0.7, 2.7] | 0.03 [0.50, 2.14] | 0.46 [0.79, 3.22] |
Severely food insecure | Ref | Ref | Ref | Ref | Ref |
Adequate minimum dietary diversity | 0.01 [−0.05, 0.07] | −0.01 [−0.08, 0.05] | 0.7 [0.5, 1.1] | 0.93 [0.64, 1.34] | 0.8 [0.5, 1.3] |
Received food assistance | −0.008 [−0.10, 0.08] | −0.003 [−0.09, 0.09] | 1.6 [0.9, 3.0]** | 1.03 [0.57, 1.86] | 1.4 [0.6, 3.4] |
Haemoglobinc, g/dl | 0.21 [0.02, 0.4]* | 0.2 [0.006, 0.40]* | 0.29 [0.10, 0.88]* | 0.4 [0.1, 1.6] | 0.9 [0.2, 4.2] |
Plasma folate concentration, nmol/L | 0.04 [−0.07, 0.14] | 0.03 [−0.06, 0.13] | 0.8 [0.4, 1.6] | 0.97 [0.50, 1.90] | 0.8 [0.3, 2.0] |
Plasma vitamin B12 concentration, pmol/L | −0.04 [−0.14, 0.07] | −0.06 [−0.17, 0.05] | 2.0 [0.99, 3.79]** | 1.2 [0.6, 2.3] | 1.4 [0.7, 2.9] |
Retinol binding protein concentrationd , μmol/L | −0.07 [−0.17, 0.03] | −0.06 [−0.16, 0.04] | 1.6 [0.8, 3.1] | 0.97 [0.5, 2.0] | 1.6 [0.6, 4.0] |
Plasma ferritin concentrationd, μg/L | −0.05 [−0.10, 0.006] | −0.05 [−0.11, 0.003]** | 1.22 [0.88, 1.71] | 1.5 [1.1, 2.0]* | 1.1 [0.8, 1.6] |
Soluble transferrin receptor concentration, mg/L | −0.05 [−0.11, 0.02] | −0.04 [−0.11, 0.03] | 1.6 [1.04, 2.5]* | 1.4 [0.8, 2.2] | 1.0 [0.6, 1.5] |
Plasma zinc concentrationd, μg/dl | −0.002 [0.006, 0.002] | −0.002 [−0.007, 0.002] | 1.0 [0.97, 1.03] | 1.0 [0.98, 1.03] | 1.03 [1.0, 1.07]** |
α‐1‐acid glycoprotein concentration, g/L | −0.10 [−0.17, −0.02]* | −0.1 [−0.2, −0.02]* | 1.7 [1.1, 2.8]* | 1.9 [1,2, 3.0]* | 1.3 [0.7, 2.3] |
C‐reactive protein concentration, mg/L | −0.002 [−0.006, −0.002]* | −0.03 [−0.06, −0.01]* | 1.14 [0.98, 1.32] | 1.2 [1.02, 1.50]* | 1.1 [1.0, 1.3] |
Plasma histidine‐rich protein II concentration, ng/L | −0.06 [−0.13, 0.002]** | −0.06 [−0.13, 0.003]** | 1.72 [1.01, 2.92]* | 1.3 [0.8, 2.2] | 1.2 [0.6, 2.3] |
Sample size for GWG analysis, n = 918, (only women in their second and third trimester of gestation at Visit 1 and who completed both Visits 1 and 2 were considered) and sample size for biochemistry indicators, n = 770.
Minimally adjusted model: adjusted for year, season, and village because of the nature of the study design.
A 0.1 g/dl in Hb concentration was associated with a 1.0‐g increase in GWG.
Adjusted for acute phase protein.
Statistically significant, P < .05.
Marginally significant; P = .05–.07.