Table I.
UPN | Age (Year) | M/F | Dx (WHO) | Date of material obtained | Transition to acute leukemia | Outcome | IPSS | IPSS-R | WBC | Neutrophils | Hb | Plt | PB-blasts (%) | BM-blasts (%) | Karyotype |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
33 | 51 | M | MDS-SLD | 2014/10/10 | No | Alive | Int-1 | Int | 5200 | 4030 | 7.6 | 135 | 0 | 0.8 | complex |
54 | 58 | F | MDS-EB1 | 2014/12/16 | No | Alive | Int-1 | Int | 2400 | 1080 | 9.3 | 74 | 0 | 5.6 | 46,XX |
59 | 55 | M | MDS-MLD | 2015/1/27 | No | Alive | Low | Very low | 4700 | 2961 | 13.7 | 56 | 0 | 0 | 46,XY |
82 | 78 | M | MDS-MLD | 2015/4/30 | No | Unknown | Int-1 | Very low | 1900 | 1267 | 10.6 | 57 | 0 | 2 | 45,X,-Y |
95 | 68 | M | MDS-SLD | 2015/8/20 | No | Unknown | Low | Low | 10200 | 7905 | 12.1 | 18 | 0 | 1.2 | 46,XY |
93 | 82 | M | MDS-SLD | 2015/8/11 | No | Dead | Low | Very low | 2200 | 1606 | 10.4 | 105 | 0 | 0 | 46,XY,del (20)(q11) |
101 | 77 | M | MDS-U based on defining cytogenetic abnormality | 2015/9/17 | No | Alive | Low | Very low | 4600 | 2852 | 10 | 30 | 0 | 0 | 45,X,-Y |
102 | 47 | F | MDS-MLD | 2015/9/30 | No | Alive | Int-1 | Low | 2800 | 1274 | 8.3 | 15 | 0 | 0 | 46,XX |
103 | 22 | M | MDS-MLD | 2015/10/9 | No | Unknown | Low | Int | 2600 | 845 | 6.3 | 21 | 0 | 0 | 46,XY |
107 | 82 | F | MDS-MLD | 2015/10/22 | No | Alive | Low | Low | 6100 | 4148 | 11.2 | 187 | 0.5 | 0.4 | 47,XX,+8 |
64_2 | 46 | F | MDS-MLD | 2016/3/8 | No | Alive | Low | Very low | 4500 | 2835 | 13.1 | 299 | 0 | 2 | 46,XX |
141 | 84 | M | MDS with isolated del(5q) | 2016/5/19 | No | Alive | Int-1 | Int | 3500 | 1295 | 9.5 | 344 | 0 | 0.5 | 46,XY,del(5q) |
115 | 50 | M | MDS-MLD | 2016/10/11 | No | Unknown | Int-1 | Low | 6600 | 5214 | 4.3 | 42 | 0.5 | 2 | 46,XY, del(11)(q14) |
8 | 72 | M | MDS-EB1 | 2014/8/8 | No | Unknown | Int-1 | High | 1700 | 408 | 9 | 78 | 0 | 5.2 | 46,XY |
12 | 38 | M | MDS-EB2 | 2014/8/26 | No | Unknown | Int-2 | High | 3000 | 1410 | 10.3 | 95 | 0.5 | 10 | 45,XY,-7 |
58 | 71 | M | MDS-EB1 | 2015/1/22 | No | Unknown | Int-2 | Very high | 2900 | 2233 | 8.3 | 31 | 0 | 9.2 | complex |
22 | 66 | M | MDS-EB1 | 2014/11/27 | Yes | Unknown | Int-1 | High | 2000 | 910 | 7.6 | 16 | 0 | 7.6 | 46,XY |
44 | 72 | M | MDS-EB2 | 2015/1/22 | Yes | Dead | High | Very high | 16300 | 2853 | 9.1 | 97 | 5 | 16.8 | 46,XY,-7,+m/46, XY,idem,del(12) (p13) |
38 | 56 | M | MDS-EB2 | 2014/10/14 | No | Dead | Int-2 | High | 5500 | 4895 | 8.3 | 164 | 0 | 12.4 | 46,XY |
120 | 68 | F | MDS-EB2 | 2016/3/10 | Yes | Dead | High | Very high | 1100 | 374 | 7.8 | 19 | 0 | 17.2 | complex |
108 | 87 | M | MDS-U with > 1% PB blasts | 2015/10/26 | No | Dead | in-2 | High | 11400 | 10864 | 8.1 | 65 | 1.5 | 4.8 | 46,XY,del(20) (q11)/46,XY, idem,-7,+8 |
175 | 68 | M | MDS-EB1 | 2016/2/3 | Yes | Dead | Int-2 | High | 2000 | 1110 | 8.8 | 30 | 2 | 4.4 | complex |
4 | 77 | M | AML with MRC | 2014/4/2 | Dead | 4500 | 393 | 8.9 | 23 | 17 | 49.5 | complex | |||
30 | 72 | M | AML with MRC | 2014/10/8 | Unknown | 800 | 248 | 7.7 | 50 | 2 | 21 | 45,X,-Y | |||
13 | 61 | M | AML (M6A) with MRC | 2014/9/10 | Dead | 1300 | 338 | 7.6 | 17 | 12 | 12.8 | complex | |||
18 | 67 | F | AML with MRC | 2014/9/16 | Dead | 2000 | 520 | 7.9 | 7 | 2.5 | 66 | 45,XX,-7 | |||
127 | 64 | M | AML with MRC | 2016/4/11 | Alive | 1300 | 240 | 9.3 | 78 | 0 | 23.2 | 46,XY | |||
133 | 67 | F | AML with MRC | 2016/4/26 | Dead | 1400 | 400 | 7.3 | 25 | 8 | 34 | 45,XX,-18 | |||
98 | 42 | F | AML with MRC | 2015/9/9 | Dead | 2000 | 270 | 11.3 | 175 | 1.5 | 21 | 46,XX,inv(16) (p13;q22)/47, XX,idem+22 |
UPN, unique patient number; M/F, male/female; Dx, diagnosis; IPSS, International Prognostic Scoring System; IPSS-R, revised IPSS; WBC, while blood cell count (×109/l); Hb, hemoglobin g/dl; Plt, platelets (×1012/l); PB, peripheral blood; BM, bone marrow; MDS, myelodysplastic syndrome; AML with MRC, acute myeloid leukemia with myelodysplasia-related changes; Unknown, due to transfer to another hospital.