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. 2020 Jan 22;48(4):2144–2155. doi: 10.1093/nar/gkz1221

Figure 7.

Figure 7.

Proposed model of RNA slippage during reiterative transcription from the pyrG promoter. Cartoon model of the active site of RNAP. pyrG ITR sequence (tDNA, −1A: purple, +1C, +2C, +3C: blue, +4G: green), nascent RNA (5′-GGG-3′, red), incoming nucleotide (GTP, cyan), active site Mg2+ (yellow sphere), trigger loop (blue shape) and RIF-binding pocket (RIF POCKET, gray) are shown. A direction of RNA extension is indicated by a dashed line.