Table 1.
Efficiency of model RPL41 mRNA recruitment to 43S PICs in individual eIF3 knockdowns compared to control NT cells from at least three biological replicates. Data from individual experiments are shown in Supplementary Table S3.
Amount of 40S bound RPL41 mRNA normalized to 18S rRNA (% relative to NT) | ||||||||
---|---|---|---|---|---|---|---|---|
NT | eIF3dKD | eIF3gKD | eIF3iKD | eIF3cKD | eIF3eKD | eIF3hKD | eIF3lKD | eIF3kKD |
100 | 47±13 | 46±13 | 55±11 | 42±10* | 78±13* | 124±14 | 124±17 | 132±27 |
*Indicates statistically significant difference (P value = 0.0007) using two-sample t-test.