Table 3.
Genes identified by MOG as showing changing expression with cancer progression (B-H corrected P-value < 0.05) that had been identified in experimental studies as potential prognostic biomarkers but were not marked as prognostic for the given cancer type in The Human Protein Atlas (THPA) (80)
| Disease | Gene | Gene name | Pattern | Ref. |
|---|---|---|---|---|
| LIHC | ARG1 | arginase 1 | Decreasing | (85) |
| LIHC | CYP2C8 | cytochrome P450 | Decreasing | (86) |
| family 2 subfamily | ||||
| C member 8 | ||||
| LIHC | CYP3A4 | cytochrome P450 | Decreasing | (87) |
| family 3 subfamily | ||||
| A member 4 | ||||
| LIHC | CYP3A7 | cytochrome P450 | Decreasing | (87) |
| family 3 subfamily | ||||
| A member 7 | ||||
| LIHC | CYP4A11 | cytochrome P450 | Decreasing | (88) |
| family 4 subfamily | ||||
| A member 11 | ||||
| THCA | CHI3L1 | chitinase 3 like 1 | Increasing | (119) |
| THCA | SFTPB | surfactant protein B | Increasing | (120) |
| THCA | CD207 | CD207 molecule | Increasing | (121) |
| THCA | MUC21 | mucin 21, cell | Increasing | (121) |
| surface associated | ||||
| THCA | MMP7 | matrix | Increasing | (122,123) |
| metallopeptidase 7 | ||||
| THCA | IGFL2 | IGF like family | Increasing | (121) |
| member 2 | ||||
| THCA | KLK7 | kallikrein related | Increasing | (124,125) |
| peptidase 7 | ||||
| THCA | FN1 | fibronectin 1 | Increasing | (126) |