Tumor sizes in the xenograft model. *P<0.05 vs. the other groups, #P<0.05 vs. control, &P<0.05 vs. control + 5-FU or control + VCR. n=4 in each group. sh, short hairpin; HSP27, heat shock 27 kD protein 1; 5-FU, 5-fluorouracil; VCR, vincristine. Scale bar=100 mm.