Table 1.
Calculation Formulas of Each Scoring System: The Sokal, Hasford, EUTOS and ELTS Scores
| Scoring System | Calculation | Risk Definition |
|---|---|---|
| Sokal score | Exp 0.0116 × (age - 43.4) + 0.0345 × (spleen - 7.51) + 0.1880 × [(platelet count/700)2-0.563] + 0.0887 × (blasts - 2.10) | Low risk: <0.8 Intermediate risk: 0.8–1.2 High risk: >1.2 |
| Hasford score | (0.6666 × age [0 when age <50 years; 1, otherwise] + 0.0420 × spleen + 0.0584 × blasts + 0.0413 × eosinophils + 0.2039 × basophils [0 when basophils <3%; 1, otherwise] + 1.0956 × platelet count [0 when platelets <1500 × 109/L; 1, otherwise]) × 1000 | Low risk: ≤780 Intermediate risk: 781–1480 High risk: >1480 |
| EUTOS score | (Basophils × 7) + (spleen × 4) | Low risk: ≤87 High risk: >87 |
| ELTS score | 0.0025 × (age/10)3 + 0.0615 × spleen + 0.1052 × blasts + 0.4104 × (platelet count/1000)−0.5 | Low risk: ≤1.5680 Intermediate risk: 1.5680–2.2185 High risk: >2.2185 |
Note: Exp, exponential function; Age is in years; Spleen is in cm below the costal margin; Platelet count is in × 109/L; Blasts, eosinophils and basophils are in percent of peripheral blood.
Abbreviations: EUTOS, European Treatment and Outcome Study; ELTS, EUTOS long-term survival.