Table 5.
Effect of the Different Solvent Fractions of T. brownii on BGL of STZ-induced Diabetic Mice
| Treatment Groups | Fasting Blood Glucose Level (mg/dL) | |||
|---|---|---|---|---|
| Day 0 | Day 5 | Day 10 | Day 15 | |
| Normal control | 160.66±7.07 | 154.00±9.02 | 144.16±17.43 | 134.50±5.32 |
| Diabetic control | 361.00±39.02 | 400.83±29.80 | 403.16±49.22 | 469.00±39.40 |
| GL 5 mg/kg | 367.66±36.02 | 234.33±30.91* | 209.33±39.04* | 133.00±17.79*** |
| AQF 500 mg/kg | 320.66±49.92 | 191.50±42.34** | 154.83±24.58*** | 144.16±24.43*** |
| ETAF 500 mg/kg | 320.33±46.57 | 253.83±39.88 | 244.16±45.27 | 190.50±33.41*** |
| BF 500 mg/kg | 396.00±44.34 | 421.33±48.52 | 417.00±40.47 | 400.33±48.79 |
Notes: The result are expressed as mean ±SEM (n=6). *p <0.05; **p <0.01; ***p <0.001 compared to diabetic control.
Abbreviations: GL, glibenclamide; AQF, aqueous residue; ETAF, ethyl acetate fraction; BF, butanol fraction.