Table II.

Univariate and multivariate analyses of prognostic parameters in patients with glioma.

	Univariate analysis		Multivariate analysis
Parameter	P-value	HR (95% CI)	P-value	HR (95% CI)
Age (≤45 vs. >45)	0.77	1.26 (0.64–1.91)	0.48	1.03 (0.51–1.67)
Sex (male vs. female)	0.64	1.09 (0.45–1.56)	0.59	1.13 (0.57–1.78)
KPS (≤90 vs.>90)	0.19	1.37 (0.84–1.98)	0.43	0.98 (0.60–1.37)
WHO grade (I–II vs. III–IV)	<0.01	7.88 (3.54–12.53)	<0.01	11.25 (5.34–19.67)
Exosomal miR-210	<0.01	3.63 (1.54–5.67)	<0.01	4.31 (1.94–8.13)

The median age was 45 years. HR, hazard ratio; KPS, Karnofsky Performance Status (49); WHO grade, World Health Organization tumor grade (2); miR-210, microRNA-210; WHO, World Health Organization.