Association between KL expression and OS/DSS. (A-C) Association between OS of 36 patients with CRPC and KL expression. (A) There was no significant association between KLA and OS. (B and C) OS was significantly lower in patients with high KLB and high KLG expression than that in patients with low KLB and low KLG expression, respectively. (D-F) Association between DSS of 36 patients with CRPC and KL expression. (D) There was no significant association between KLA and DSS. (E and F) DSS was significantly lower in patients with high KLB and high KLG expression than that in patients with low KLB and low KLG expression, respectively. KL, Klotho; OS, overall survival; DSS, disease-specific survival; CRPC, castration-resistant prostate cancer; KLA, α-Klotho; KLB, β-Klotho; KLG, γ-Klotho.