Table VI.

Relative fold mRNA expression value level (2^−ΔΔCq) of molecules involved in the Wnt signaling pathway and E-cadherin based on the expression levels of the target gene vs. the reference housekeeping gene B2M between specific subgroups of thymomas.

		CTNNB1		CCND1		MYC		AXIN2		CDH1
Subgroups	n	Value	P-value	Value	P-value	Value	P-value	Value	P-value	Value	P-value
Invasivity, Inv./Non-inv.	71/41	1.28±0.30	0.144	2.28±0.94	0.006a	1.85±0.53	0.017a	0.64±0.43	0.113	2.55±1.69	0.0012a
Age, <60/>60	65/47	1.49±0.31	0.027a	1.57±1.10	0.087	1.88±0.70	0.020a	1.21±0.21	0.316	1.42±0.99	0.102
Recurrence, Rec./No rec.	9/103	2.28±0.85	0.044a	2.64±0.67	<0.001a	0.97±0.48	0.452	2.16±0.88	0.124	3.61±0.51	0.015a

^aSignificant. Inv., invasive; Non-inv., non-invasive; Rec., recurrent cases; No rec., No recurrence.