Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Dec 24;219(1):e201907060. doi: 10.1083/jcb.201907060

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Greenan et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 5. — TMT-to-DMT conversion happens within the BB and correlates with changes to the outer BC junction. Subvolumes of the BB class were further classified based on their C-tubules, resulting in three major classes. (A) In one class (∼23%), the C-tubule was complete and had an MIP bound to protofilament C02. (B) A second class (∼24%) containing a partial C-tubule was also observed, but this class lacked the C02-bound MIP. (C) The final class (∼25%) contained no detectable C-tubule density. (D and E) When viewed from inside (plane of view defined by the dashed lines and double arrowheads in A and B), the C01 position was continuous in the TMT class (D) but periodic (8 nm) in the partial TMT class (E). (F) The differences at the outer BC junction, and the similarities in the A- and B-tubule MIPs, can be appreciated in the overlay. (G) A refit of the three BB classes back into the whole cilium shows the transition from TMTs to DMTs. Scale bars are 25 nm (A–F); 100 nm (G).