Table 1.
Cocaine use disorder | Healthy controls | |
---|---|---|
n = 24 | n = 25 | |
Age | 40 ± 9 | 37 ± 9 |
Sex | ||
Females | 10 | 11 |
Males | 14 | 14 |
Ethnicity | ||
African American | 10 | 5 |
Caucasian | 12 | 18 |
Asian | 0 | 1 |
Hispanic | 1 | 0 |
More than one race | 1 | 1 |
Barratt Simplified Measure of Social Status | ||
Education | 14 ± 3 | 15 ± 4 |
Occupation | 21 ± 10 | 27 ± 4* |
Total | 33 ± 13 | 42 ± 12* |
Tobacco use | 16 | 13 |
> 10 cigarettes per day | 7 | 4 |
Cannabis use (recreational) | 4 | - |
Hamilton Anxiety Rating Scale (range 0 to 56) | 8.5 ± 7.5 | 2.1 ± 3.7* |
Perceived Stress Scale (range 0 to 40) | 15.2 ± 7.8 | 5.5 ± 5.3* |
Cocaine Craving Questionnaire (range 0 to 70) | 26 ± 15 | |
Age of first use of cocaine (years) | 23 ± 8 | |
Duration of cocaine use (years) | 15 ± 9 | |
Cocaine use frequency per week (days) | 2 ± 2 | |
Amount spent on cocaine per week (dollars) | 126 ± 64 | |
12-week follow-up protocol to monitor for relapse following PET scan | ||
Final Outcome | ||
Abstinent | 6 | |
Relapsed (cocaine +) | 9 | |
Drop-out | 9 | |
Amount of money earned in vouchers (dollars) | 415 ± 476 | |
Time to an event, i.e., first relapse or drop-out or completion (days) | 35 ± 34 | |
Time to first relapse (days) | 13 ± 14 | |
Duration in follow-up protocol (days) | 43 ± 35 |
p < 0.05, unpaired t-tests for numerical variables and Chi-square test for categorical variables.