Table 2.
[11C]NOP-1A scan parameters
| Scan Parameter | Cocaine use disorder n = 24 |
Healthy controls n=25 |
|---|---|---|
| Injected dose (mCi) | 12.4 ± 0.7 | 12.3 ± 1.0 |
| Specific Activity (Ci/mmoles) | 2169 ± 975 | 2230 ± 558 |
| Injected mass (μg) | 2.8 ± 1.0 | 2.5 ± 0.6 |
| Plasma free fraction (fP, %) † | 14.5% ± 3.2% | 13.2% ± 2.3% |
| Plasma free fraction buffer (fP, %) † | 71.0% ± 15.7% | 76.1% 11.5% |
| Clearance (L/h) | 151.8 ± 38.9 | 155.1 ± 38.1 |
Values are mean ± SD in cocaine use disorder and healthy control subjects
SD - Standard deviation
†
Data was only available from n=23 CUD and 22 HC due to problems with sample processing.