Table 1.
Proteins that interact with endothelial nitric oxide synthase.
Protein | Effect of Bound Protein | References |
---|---|---|
Calmodulin | Activating | 6,7,8,9,10 |
Hsp90 | Activating | 13, 14, 15, 16, 17, 18, 19, 20 |
Dynamin-2 | Activating | 33, 34 |
G-actin | Activating | 41, 43, 44, 52, 53 |
Tubulin | Activating | 40 |
Porin | Activating | 57, 58 |
HDL and ApoAI | Activating | 59 |
Calveolin | Inhibiting | 62, 63, 64, 65, 66 |
GPCR | Inhibiting | 68, 69 |
NOSIP | Inhibiting and trafficking | 54, 70 |
NOSTRIN | Inhibiting and trafficking | 38, 51, 72, 73, 74 |
F-actin | Trafficking | 51, 54 |
CAT-1 | Substrate delivering | 84 |
ASS and ASL | Substrate delivering | 88, 89 |
sGC | NO target | 91 |
HDL (high-density lipoprotein); ApoAI (apolipoprotein AI), GPCR (G protein-coupled receptors); NOSIP (nitric oxide synthase-interacting protein); NOSTRIN (nitric oxide synthase trafficking inducer); CAT-1 (cationic amino acid transporter-1); ASS (argininosuccinate synthase); ASL (argininosuccinate lyase); sGC (soluble guanylate cyclase).