Table 1.

Clinical questions for the CDC pediatric mTBI guideline (Lumba-Brown et al., 2018).

1. For children (18 years of age and younger) with suspected mTBI, do specific tools, as compared with a reference standard, assist in accurately diagnosing mTBI?

2. For children (18 years of age and younger) presenting to the emergency department (or other acute care setting) with mTBI, how often does routine head imaging identify intracranial injury?

3. For children (18 years of age and younger) presenting to the emergency department (or other acute care setting) with mTBI, which features identify patients at risk for important intracranial injury (iICI)?

4. For children (18 years of age and younger) with mTBI, what factors identify patients at increased risk for ongoing impairment, more severe symptoms, or delayed recovery (< 1 year post-injury)?

5. For children (18 years of age and younger) with mTBI, which factors identify patients at increased risk of long-term (≥1 year) sequelae?

6. For children (18 years of age and younger) with mTBI (with ongoing symptoms), which treatments improve mTBI-related outcomes?