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. 2020 Feb 24;15(2):e0229484. doi: 10.1371/journal.pone.0229484

Table 1. Patient characteristics in the sex-and-age-matched and propensity-score-matched cohorts for the COPD with asthma cohort and COPD cohort.

Age and Sex Matched Propensity Score Matched
Variable COPD with asthma cohort COPD cohort COPD with asthma cohort COPD cohort
(N = 12,538) (N = 25,069) (N = 9902) (N = 9902)
n % n % p-value n % n % p-value
Age, year 0.99 0.001
    20−49 2050 16.4 4100 16.4 1510 15.3 1672 16.9
    50−64 3498 27.9 6996 27.9 3007 30.4 2709 27.4
    ≥ 65 6990 55.8 13973 55.7 5385 54.4 5521 55.8
    Mean (SD)# 64.9 14.4 64.7 14.4 0.37 64.9 14.7 64.8 13.9 0.01
Gender 0.98 0.89
    Female 5403 43.1 10805 43.1 4379 44.2 4389 44.3
    Male 7135 56.9 14264 56.9 5523 55.8 5513 55.7
Comorbidity
    Diabetes 1752 14.0 3273 13.1 0.01 1424 14.4 1452 14.7 0.57
    Hypertension 7689 61.3 12107 48.3 <0.001 6084 61.4 6119 61.8 0.89
    Hyperlipidemia 3832 30.6 6095 24.3 <0.001 3066 31.0 3075 31.1 0.89
    Mental disorders 6455 51.5 8491 33.9 <0.001 5080 51.3 5111 51.6 0.66
    Chronic kidney disease 336 2.68 654 2.61 0.68 279 2.82 284 2.87 0.83
    Cardiovascular disease 6382 50.9 8341 33.3 <0.001 5080 51.3 5111 51.6 0.66
Medication
    Inhaled corticosteroids (ICSs) 3204 25.6 814 3.25 <0.001 568 5.74 568 5.74 0.99
    Oral steroids (OSs) 9791 78.1 10721 42.8 <0.001 7386 74.6 7377 74.5 0.88

SD, standard deviation.

Chi-square test

#t test