Table 1. Patient characteristics in the sex-and-age-matched and propensity-score-matched cohorts for the COPD with asthma cohort and COPD cohort.
Age and Sex Matched | Propensity Score Matched | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Variable | COPD with asthma cohort | COPD cohort | COPD with asthma cohort | COPD cohort | ||||||
(N = 12,538) | (N = 25,069) | (N = 9902) | (N = 9902) | |||||||
n | % | n | % | p-value | n | % | n | % | p-value | |
Age, year | 0.99 | 0.001 | ||||||||
20−49 | 2050 | 16.4 | 4100 | 16.4 | 1510 | 15.3 | 1672 | 16.9 | ||
50−64 | 3498 | 27.9 | 6996 | 27.9 | 3007 | 30.4 | 2709 | 27.4 | ||
≥ 65 | 6990 | 55.8 | 13973 | 55.7 | 5385 | 54.4 | 5521 | 55.8 | ||
Mean (SD)# | 64.9 | 14.4 | 64.7 | 14.4 | 0.37 | 64.9 | 14.7 | 64.8 | 13.9 | 0.01 |
Gender | 0.98 | 0.89 | ||||||||
Female | 5403 | 43.1 | 10805 | 43.1 | 4379 | 44.2 | 4389 | 44.3 | ||
Male | 7135 | 56.9 | 14264 | 56.9 | 5523 | 55.8 | 5513 | 55.7 | ||
Comorbidity | ||||||||||
Diabetes | 1752 | 14.0 | 3273 | 13.1 | 0.01 | 1424 | 14.4 | 1452 | 14.7 | 0.57 |
Hypertension | 7689 | 61.3 | 12107 | 48.3 | <0.001 | 6084 | 61.4 | 6119 | 61.8 | 0.89 |
Hyperlipidemia | 3832 | 30.6 | 6095 | 24.3 | <0.001 | 3066 | 31.0 | 3075 | 31.1 | 0.89 |
Mental disorders | 6455 | 51.5 | 8491 | 33.9 | <0.001 | 5080 | 51.3 | 5111 | 51.6 | 0.66 |
Chronic kidney disease | 336 | 2.68 | 654 | 2.61 | 0.68 | 279 | 2.82 | 284 | 2.87 | 0.83 |
Cardiovascular disease | 6382 | 50.9 | 8341 | 33.3 | <0.001 | 5080 | 51.3 | 5111 | 51.6 | 0.66 |
Medication | ||||||||||
Inhaled corticosteroids (ICSs) | 3204 | 25.6 | 814 | 3.25 | <0.001 | 568 | 5.74 | 568 | 5.74 | 0.99 |
Oral steroids (OSs) | 9791 | 78.1 | 10721 | 42.8 | <0.001 | 7386 | 74.6 | 7377 | 74.5 | 0.88 |
SD, standard deviation.
Chi-square test
#t test