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. 2020 Jan 15;8(1):e000991. doi: 10.1136/bmjdrc-2019-000991

Table 2.

Associations of CKD with distal peripheral neuropathy

CKD
(n=81)
Controls
(n=24)
P value* Adjusted difference
(95% CI)†
Adjusted OR
(95% CI)†
Mean MNSI questionnaire score 3.36 (2.97) 2.33 (2.41) 0.046 1.35 (0.03 to 2.67)
MNSI score ≥2‡ 51 (63%) 11 (46%) 0.160 2.29 (0.88 to 6.00)
MNSI score ≥2 or use of one or more neuropathy medications 56 (69%) 13 (54%) 0.222 2.31 (0.86 to 6.20)
MNSI score ≥4 36 (44%) 8 (33%) 0.358 2.16 (0.78 to 5.94)

*Unadjusted t-test or χ2 test.

†Adjusted for age, gender, race

‡ Primary outcome of interest.

CKD, chronic kidney disease; MNSI, Michigan Neuropathy Screening Instrument.