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. Author manuscript; available in PMC: 2020 Feb 24.
Published in final edited form as: Mol Psychiatry. 2017 Dec 12;23(9):1929–1936. doi: 10.1038/mp.2017.234

Figure 3.

Figure 3.

Pooled results correlating MPH efficacy to VNTRs. Forest plots of association between MPH efficacy and the following DNA variants: (a) DRD4 4-repeat; (b) DRD4 7-repeat; (c) SLC6A3 10-repeat. Each forest plot represents one genetic variant and its computed effect size (odds ratio, measure of precision and P-value). Red squares are proportional to the studies’ weights and horizontal black bars represent the corresponding 95% confidence interval (precision measurement) for each study. The vertical line at 1 indicates the null effect line and represents no differences between groups. The location of the black box represents the direction and magnitude of the pooled odds ratio that was generated from a fixed-effect model; its width represents the upper and lower bounds of the 95% confidence interval. Assessments of heterogeneity by χ2 and I2 are located on the left of each forest plot. A P-value is given for a test of the null. MPH, methylphenidate.