Table 6.
Multivariable regressions of telomere length vs. weighted individual SNP and weighed genetic sum score, stratified by TB
| SNP | Gene | Effect allele (short TL) | TB positive | TB negative | ||||
|---|---|---|---|---|---|---|---|---|
| Adjusted β | 95%CI | p-value | Adjusted β | 95%CI | p-value | |||
| rs10936599 | TERC | T | −0.019 | (−0.05, 0.012) | 0.23 | 0.007 | (−0.019, 0.033) | 0.59 |
| rs7675998 | NAF1 | A | 0.004 | (−0.058, 0.065) | 0.90 | −0.014 | (−0.067, 0.04) | 0.62 |
| rs9420907 | OBFC1 | A | −0.0002 | (−0.006, 0.005) | 0.93 | −0.007 | (−0.012, −0.003) | 0.002 |
| rs8105767 | ZNF208 | A | −0.02 | (−0.057, 0.017) | 0.29 | 0.009 | (−0.028, 0.045) | 0.64 |
| rs755017 | RTEL1 | A | −0.008 | (−0.016, 0.001) | 0.08 | −0.002 | (−0.01, 0.006) | 0.59 |
| rs2736100 | TERT | A | 0.004 | (−0.008, 0.015) | 0.52 | −0.011 | (−0.021, −0.001) | 0.03 |
| Genetic sum score | −0.002 | (−0.006, −0.002) | 0.38 | −0.006 | (−0.01, −0.003) | 0.001 | ||