Table 4. Per-Lesion Diagnostic Performance of Abbreviated MRI Sequence(s) for Hepatic Malignancy.
| Diagnostic Criteria | Sensitivity (%)* | P† | Specificity (%)* | P† | Accuracy (%)* | P† |
|---|---|---|---|---|---|---|
| One or more findings∥ | ||||||
| T2WI | 86.8 [77.1–93.5] | 0.296‡ | 92.0 [83.4–97.0] | All > 0.950‡ | 89.4 [83.4–93.8] | 0.470‡ |
| DWI | 90.8 [81.9–88.8] | 0.359‡ | 96.0 [88.8–99.2] | 93.4 [88.2–96.8] | 0.595‡ | |
| HBP | 93.4 [85.3–97.8] | 0.709‡ | 94.7 [86.9–98.5] | 94.0 [89.0–97.2] | 0.835‡ | |
| T2WI, Dual-GRE | 89.5 [80.3–95.3] | 0.434 | 92.0 [83.4–97.0] | 90.7 [84.9–94.8] | 0.592 | |
| DWI, Dual-GRE | 93.4 [85.3–97.8] | 0.508‡ | 94.7 [86.9–98.5] | 94.0 [89.0–97.2] | 0.768‡ | |
| HBP, Dual-GRE | 94.7 [87.1–98.6] | 94.7 [86.9–98.5] | 94.7 [89.8–97.7] | |||
| Two or more findings | ||||||
| T2WI, HBP | 86.8 [77.1–93.5] | 0.544§ | 96.0 [88.8–99.2] | All > 0.970§ | 91.4 [85.7–95.3] | 0.721§ |
| DWI, HBP | 89.5 [80.3–95.3] | 0.723§ | 97.3 [90.7–99.7] | 93.4 [88.2–96.8] | 0.942§ | |
| T2WI, DWI | 84.2 [74.0–91.6] | 0.458§ | 97.4 [90.7–99.7] | 90.7 [84.9–94.8] | 0.657§ | |
| T2WI, DWI, Dual-GRE | 86.8 [77.1–93.5] | 0.610§ | 97.3 [90.7–99.7] | 92.1 [86.5–95.8] | 0.831§ | |
| T2WI, DWI, Dual-GRE, HBP | 92.1 [83.6–97.1] | 93.3 [85.1–97.8] | 92.7 [87.3–96.3] |
Numbers in square brackets are 95% confidence intervals. *Percentage out of 151 nodules, †Bonferroni-correct p values, ‡Compared to combination of HBP and Dual-GRE, §Compared to combination of all four sequences, ∥Phrase “One or more findings” refers to presence of more than one finding among eight imaging features, known to favor diagnosis of HCC.