Table 2. Results of Univariable and Multivariable Cox-Proportional Hazard Model for Evaluating Factors Associated with Overall Survival of 60 Patients after RFA.
Variable | Univariable Cox Regression Analysis | Multivariable Cox Regression Analysis | ||||
---|---|---|---|---|---|---|
Hazard Ratio | 95% CI | P | Adjusted Hazard Ratio | 95% CI | P | |
Age (> 60.5 years, n = 30) | 1.03 | 0.61–1.74 | 0.912 | NA | NA | NA |
Sex (male) | 1.34 | 0.78–2.29 | 0.291 | NA | NA | NA |
TNM stage (≥ IIB) | 2.06 | 1.13–3.75 | 0.018 | 2.73 | 1.47–5.07 | 0.001 |
Poorly differentiated | 2.30 | 1.10–4.81 | 0.027 | 2.10 | 0.99–4.44 | 0.052 |
Tumor number (≥ 2) | 1.46 | 0.84–2.52 | 0.179 | NA | NA | NA |
Tumor size (> 1.5 cm) | 2.16 | 1.25–3.73 | 0.006 | 2.19 | 1.24–3.89 | 0.007 |
Period to recurrence (< 1 year) | 1.88 | 0.99–3.57 | 0.055 | 2.26 | 1.16–4.38 | 0.016 |
Presence of extrahepatic metastasis | 3.81 | 1.79–8.07 | < 0.001 | 3.37 | 1.57–7.20 | 0.002 |
CI = confidence interval, NA = not applicable