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. Author manuscript; available in PMC: 2021 Mar 15.
Published in final edited form as: Hear Res. 2020 Jan 3;388:107880. doi: 10.1016/j.heares.2019.107880

Figure 1:

Figure 1:

HK-2 prevents NIHL. (A) Schematic of 21-d noise and schedule of dosing for HK-2 Prevention treatment (36 days) and HK-2 Rescue treatment (10 days post-exposure). (B) Spectrum of 95.5 dB SPL, 8–16 kHz (1.5 Hz/bin) noise presented 8 hours/day for 21 days. Mean (SEM) CAP I/O functions for 12 kHz (C-E) and 30 kHz F-H) CAP thresholds shifts as a function of frequency in Noise group vs. Noise+HK-2 group (see legend in each panel). Threshold shifts in HK-2 treated group significantly less than in Noise groups (see text for details).