Figure 6.

Graphs showing the ratio of variance unexplained by each variable when fitting a linear regression model with sex to predict circumpapillary retinal nerve fiber layer thickness, as explained by the standard analysis of variance (ANOVA) formula in “Methods.” The 2 identical subplots in the first row were added as a spatial marker and illustrate the locations where retinal nerve fiber layer thickness (RNFLT) is significantly thicker in males (blue) or females (red). The other 6 subplots in rows 2 through 4 depict ANOVA results at these significant locations for age, scanning radius, body height, superotemporal peak location, inferotemporal peak location, and interpeak angle, respectively. The percent variance plots (i.e., the black shaded areas in each subplot) denote the percentages of variance explained by sex that was not already explained by the respective parameter. For instance, in the age subplot (second row, first column), a percent variance value of 60% means that for the respective circumpapillary location, 60% of the explained variance of the regression model RNFLT equals approximately age plus sex was explained by sex and 40% by age. Locations without significant sex effects (i.e., all locations shown in black in the top row) were omitted in this analysis. IN = inferonasal; Inf. = inferior; IT = inferotemporal; N = nasal; SN = superonasal; ST = superotemporal; Sup. = superior; T = temporal.