Table 7.
Preoperative liver function parameters in post-hepatectomy liver failure and non-post-hepatectomy liver failure patients who did not have hepatitis viruses in univariate analysis
| Factors |
No postoperative liver failure |
Postoperative liver failure |
Univariate analysis |
|
| (n = 136) | (n = 22) | OR (95%CI) | P value | |
| Age, yr (mean) | 65.3 | 70.7 | 0.09 | |
| Sex, male/female | 87/49 | 4/18 | 0.109 | |
| Preoperative biliary drainage | 9 | 4 | 0.045 | |
| Child-Pugh score | 5.15 ± 0.39 | 5.59 ± 0.80 | 3.694 (1.766-7.729) | 0.001 |
| Platelets (× 104/μL) | 21.1 ± 7.7 | 17.1 ± 7.0 | 0.991 | |
| Total bilirubin (mg/dL) | 0.79 ± 0.33 | 0.91 ± 0.40 | 0.111 | |
| PT-INR (INR) | 0.99 ± 0.13 | 1.1 ± 0.14 | 123.581 (2.637-5791.435) | 0.014 |
| Albumin (g/dL) | 4.03 ± 0.44 | 3.57 ± 0.60 | 0.157 (0.059-0.414) | < 0.001 |
| Aspartate aminotransferase (IU/L) | 30.8 ± 26.6 | 41.5 ± 25.9 | 0.121 | |
| Alanine aminotransferase (IU/L) | 28.0 ± 22.9 | 33.6 ± 25.5 | 0.296 | |
| Cholinesterase (IU/L) | 293.1 ± 85.1 | 192.2 ± 67.9 | 0.979 (0.970-0.988) | < 0.001 |
| Total cholesterol (mg/dL) | 192.2 ± 42.2 | 168.4 ± 40.2 | 0.985 (0.973-0.998) | 0.02 |
| ICG-15 clearance rate (%) | 10.3 ± 9.11 | 15.0 ± 11.8 | 1.034 (0.998-1.081) | 0.064 |
| Type IV collagen 7S (ng/mL) | 5.36 ± 1.85 | 9.15 ± 3.13 | 1.731 (1.383-2.167) | < 0.001 |
| Hyaluronic acid (ng/mL) | 78.7 ± 99.2 | 261.9 ± 207.3 | 1.005 (1.004-1.011) | < 0.001 |
| ARFITM (v/s) | 1.49 ± 0.53 | 1.98 ± 0.67 | 2.785 (1.546-7.887) | 0.003 |
| CRP (mg/dL) | 0.47 ± 1.14 | 1.00 ± 1.42 | 0.056 | |
| Extent of hepatic resection[26] | 0.90 ± 1.0 | 1.41 ± 1.05 | 1.638 (1.037-2.587) | 0.034 |
PT-INR: Prothrombin time-international normalized ratio; ICG-R15: Indocyanine green retention rate at 15 min; ARFI: Acoustic radiation force impulse; CRP: C-reactive protein.