Figure 3.

Neonatal murine lung CD103⁺ DCs and CD11b⁺ DC subsets demonstrate distinct basal co-stimulatory molecule expression. (A) Similar antigen uptake capacity of neonatal and adult APCs was noted across all the DC subsets. (B–D) Neonatal CD103⁺ DCs and CD11b⁺ lung DC subsets demonstrate a lower expression of co-stimulatory molecules CD40, CD80, and CD86 as compared to adult mice. Results are expressed as mean ± SEM of n = 12 per age group. **p < 0.01, ***p < 0.001 determined by repeated measures two-way ANOVA with Sidak post-hoc test.