Table 2.
Inhibition and potency data from the final hits (Coutard et al., 2014).
| DENV 2'O-Mtase activity inhibition (%) | DENV 2'O-MTase activity IC50 (mM) | |
|---|---|---|
| 81 | 4 | 3.90 ± 0.16 |
| 91 | 11 | 2.83 ± 0.18 |
| 95 | 85 | 0.18 ± 0.01 |
| 157 | 9 | 9.39 ± 0.90 |
| 217 | 11 | 3.12 ± 0.27 |
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