Table 1.
P16-positivity (p16 +), TILs ≥ 50% and high PD-L1 expression (TPS 5, ICS 3 and CPS ≥ 50) in correlation to patients characteristics and the overall survival (n = 128)
| Variables | Total (%) | p16 + | TILs ≥ 50% | PD-L1 TPS 5 (≥ 50%) | PD-L1 ICS 3 (≥ 10%) | PD_L1 CPS ≥ 50 |
|---|---|---|---|---|---|---|
| Total (%) | 50 (39) | 31 (24) | 24 (19) | 57 (45) | 25 (20) | |
| Age | ||||||
| < 70 years | 57 (45) | 32 (64) | 16 (52) | 14 (58) | 25 (44) | 14 (56) |
| ≥ 70 years | 71 (55) | 18 (36) | 15 (48) | 10 (42) | 32 (56) | 1 1 (44) |
| p value | – | < 0.001 | 0.362 | 0.131 | 0.891 | 0.198 |
| Grading | ||||||
| G1 | 17 (13) | 3 (6) | 4 (13) | 0 (0) | 9 (16) | 0 (0) |
| G2 | 77 (60) | 33 (66) | 21 (68) | 14 (58) | 37 (65) | 15 (60) |
| G3 | 34 (27) | 14 (28) | 6 (19) | 10 (42) | 11 (19) | 10 (40) |
| p value | – | 0.149 | 0.550 | 0.028 | 0.233 | 0.031 |
| FIGO | ||||||
| FIGO I | 36 (28) | 18 (36) | 12 (39) | 5 (21) | 16 (28) | 6 (24) |
| FIGO II | 52 (41) | 19 (38) | 11 (36) | 9 (38) | 23 (40) | 8 (32) |
| FIGO III | 31 (24) | 9 (18) | 7 (23) | 9 (38) | 13 (23) | 10 (40) |
| FIGO IV | 9 (7) | 4 (8) | 1 (3) | 1 (4) | 5 (9) | 1 (4) |
| p value | – | 0.338 | 0.426 | 0.373 | 0.992 | 0.225 |
| Overall survival (univariate analysis) | ||||||
| p value | < 0.001 | 0.130 | 0.465 | 0.599 | 0.133 | |