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. 2020 Jan 17;12(1):25–39. doi: 10.1007/s12551-020-00621-8

Fig. 3.

Fig. 3

a Representative α-substituted L-Pro analogs discussed in this article (see Table S1 for structural details). b A schematic showing the effect (steric clash in the cis conformation) of α-substitution on cis/trans equilibrium. c A schematic showing the effect (steric clash in the endo puckered state) of α-substitution on endo/exo equilibrium. d Ramachandran plot for α-substituted L-Pro and D-Pro analogs (circle trans; triangle cis)