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. 2019 Dec 2;66(1):1–7. doi: 10.1262/jrd.2019-102

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Fig. 2. — A chart summarizing described in the literature interactions between lipids and glucose metabolism after modifications of cumulus-oocyte complexes (COCs) maturation environment. Lines 1 to 3 – maturation media are supplemented with non-estrified fatty acids (NEFA) or glucose in concentrations higher or lower than physiological. Line 4 – fatty acid oxidation is induced via supplementation of maturation media with carnitine. Lines 5 to 7 – fatty acid oxidation is inhibited via supplementation of maturation media with etomoxir. Variable effects of the described in vitro maturation (IVM) modifications within the oocyte, cumulus cells or blastocysts are summarized. The legend of the graphic signs used in the chart is present in the line 8.