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STAT3 and STAT5b mutations described in T-LGLL and CLPD-NK. The STAT3 and STAT5b mutations, reported up to now in literature (13–32), are indicated on their position in the exon upstream the corresponding protein domain. The point mutations and the insertions/deletions are reported above and below the schematic representation of the gene, respectively. ND, N-terminal domain; CCD, coiled-coil domain; DBD, DNA binding domain; L, linker; SH2, Src Homology 2; TAD, transactivation domain.
