TABLE 2.
Tissue nitric oxide, peroxynitrite and cyclic guanylate cyclize levels.
| Parameter | Y-C | O-S | O-CR | O-PE | O-CR-PE |
| NOx (nmol/mg protein) | 145 ± 7.2 | 348 ± 22.3∗ | 188 ± 11.6*,& | 193 ± 20.3*,& | 175 ± 12.4*,& |
| ONO2–(nmol/g tissue) | 114 ± 3.1 | 208 ± 18.2∗ | 150 ± 32.3*,& | 164 ± 29.8*,& | 134 ± 24.9*,& |
| cGMP (pmol/mg protein) | 12.98 ± 0.32 | 8.57 ± 0.12∗ | 11.41 ± 0.25& | 11.03 ± 0.12& | 12.24 ± 0.18& |
p < 0.05 ∗ compared to Y-C; & compared to O-S; n = 6. NO, nitrite/nitrate, ONO2–, peroxynitrite, cGMP, cyclic guanylate cyclize; Y-C, young control; O-S, old sedentary; O-CR, old calorie restricted; O-PE, old exercise treated; O-CR-PE, old calorie restricted and exercise treated.