TABLE 5.
Conservation of significantly (p < 0.05; q < 0.1) exercise-induced metabolite changes at 3 h post-exercise.
Metabolite name | Pathway |
Fold change (FC)* |
|
UC (n = 8) | C (n = 8) | ||
N-methylalanine | Alanine and aspartate | 3.58 | 1.80 |
4-methyl-2-oxopentanoate | BCAA | 2.02 | 1.75 |
2-hydroxy-3-methylvalerate | BCAA | 2.01 | 2.45 |
3-methyl-2-oxobutyrate | BCAA | 1.79 | 1.99 |
Alpha-hydroxyisovalerate | BCAA | 1.75 | 2.92 |
Beta-hydroxyisovalerate | BCAA | 1.39 | 1.47 |
Saccharopine | Lysine | 3.62 | 8.38 |
2-aminoadipate | Lysine | 3.38 | 2.55 |
2-hydroxybutyrate/2-hydroxyisobutyrate | Methionine, cysteine, SAM and taurine | 1.29 | 1.58 |
3-(4-hydroxyphenyl)lactate | Phenylalanine and tyrosine | 1.79 | 2.15 |
Phenyllactate (PLA) | Phenylalanine and tyrosine | 1.50 | 1.85 |
Indolelactate | Tryptophan | 1.81 | 4.16 |
Mannitol/sorbitol | Carbohydrate | 1.82 | 3.14 |
Sedoheptulose | Carbohydrate | 1.91 | 4.18 |
Arachidoylcarnitine (C20) | Lipid | 4.46 | 3.32 |
3-hydroxybutyrylcarnitine (2) | Lipid | 2.44 | 2.47 |
3-hydroxybutyrylcarnitine (1) | Lipid | 1.64 | 1.55 |
2-hydroxyadipate | Lipid | 1.98 | 3.20 |
N-palmitoyl-sphinganine (d18:0/16:0) | Lipid | 1.89 | 1.94 |
Urate | Nucleotide | 5.58 | 10.72 |
AICA ribonucleotide | Nucleotide | 3.53 | 6.93 |
Xanthosine | Nucleotide | 1.97 | 2.51 |
Quinolinate | Vitamin | 2.74 | 5.83 |
Methyl 4-hydroxybenzoate sulfate | Xenobiotic | 3.56 | 13.71 |
Propyl 4-hydroxybenzoate sulfate | Xenobiotic | 3.07 | 14.94 |
Quinate | Xenobiotic | 2.20 | 1.87 |
*Fold change values are normalized to the pre-exercise time point for each respective group.