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. 2020 Feb 18;11:110. doi: 10.3389/fphys.2020.00110

TABLE 5.

Conservation of significantly (p < 0.05; q < 0.1) exercise-induced metabolite changes at 3 h post-exercise.

Metabolite name Pathway Fold change (FC)*
UC (n = 8) C (n = 8)
N-methylalanine Alanine and aspartate 3.58 1.80
4-methyl-2-oxopentanoate BCAA 2.02 1.75
2-hydroxy-3-methylvalerate BCAA 2.01 2.45
3-methyl-2-oxobutyrate BCAA 1.79 1.99
Alpha-hydroxyisovalerate BCAA 1.75 2.92
Beta-hydroxyisovalerate BCAA 1.39 1.47
Saccharopine Lysine 3.62 8.38
2-aminoadipate Lysine 3.38 2.55
2-hydroxybutyrate/2-hydroxyisobutyrate Methionine, cysteine, SAM and taurine 1.29 1.58
3-(4-hydroxyphenyl)lactate Phenylalanine and tyrosine 1.79 2.15
Phenyllactate (PLA) Phenylalanine and tyrosine 1.50 1.85
Indolelactate Tryptophan 1.81 4.16
Mannitol/sorbitol Carbohydrate 1.82 3.14
Sedoheptulose Carbohydrate 1.91 4.18
Arachidoylcarnitine (C20) Lipid 4.46 3.32
3-hydroxybutyrylcarnitine (2) Lipid 2.44 2.47
3-hydroxybutyrylcarnitine (1) Lipid 1.64 1.55
2-hydroxyadipate Lipid 1.98 3.20
N-palmitoyl-sphinganine (d18:0/16:0) Lipid 1.89 1.94
Urate Nucleotide 5.58 10.72
AICA ribonucleotide Nucleotide 3.53 6.93
Xanthosine Nucleotide 1.97 2.51
Quinolinate Vitamin 2.74 5.83
Methyl 4-hydroxybenzoate sulfate Xenobiotic 3.56 13.71
Propyl 4-hydroxybenzoate sulfate Xenobiotic 3.07 14.94
Quinate Xenobiotic 2.20 1.87

*Fold change values are normalized to the pre-exercise time point for each respective group.