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. 2020 Feb 18;11:109. doi: 10.3389/fphys.2020.00109

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Copyright © 2020 Tan, Lee, Chen and Huizinga.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Motor patterns associated with pellet expulsion with Krebs perfusion. (A) Movement of the pellet into the distal colon by the peristaltic reflex. (B) Movement of the pellet into the distal colon by regularly occurring CMC. After traveling a partial length of the colon, the pellet may stop at one point for several minutes. It is eventually dislodged by intrinsic CMCs, which allow the pellet to become expelled at the anal end. Throughout this process, the frequencies of these CMCs do not change. (C) Spatiotemporal map of (A). (D) Spatiotemporal map of (B).