Figure 3.

ELK3 knockdown inhibits the growth of xenograft tumor in vivo. DU145 cells transfected with NC-siRNA and ELK3-siRNA were injected subcutaneously into nude mice (4 mice for each group), respectively. (a) Tumor formation in the indicated time points (up table); tumor volume (lower graph). (b) Representative images of tumors formed in nude mice (up panel); tumor weight after sacrifice (lower panel). Data were averaged from 4 mice, and given as mean ± SD. ^∗P < 0.05, ^∗∗P < 0.01, vs NC-siRNA.