Table 1. Sample characteristics in 518 children and adolescents with ADHD.
| Total Sample | Sex | ADHD subtype | Age of onset* | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Boys | Girls | p | IA | C | p | Children | Adolescents | p | ||
| Age mean (SD) years | 11.40 (3.3) | 11.38 (3.2) | 11.5 (3.69) | > .1 | 11.9 (3.4) | 11.2 (3.2) | .027* | 8.9 (1.7) | 14.6 (1.8) | <.001 |
| Follow-up, months | 33 (22.7) | 32.4 (23.2) | 35.3 (20.7) | > .1 | 31.4 (20.8) | 33.7 (23.6) | > .1 | 37.7 (25.1) | 27 (17.7) | <.001 |
| ADHD-RS-IV.es | ||||||||||
| T1 ADHD-RS-IV (SD) | 29.9 (10.42) | 30.71 (10.5 | 26.7 (9.6) | <.001 | 28.82 (10.6) | 30.4 (10.3) | 31.7 (10) | 27.6 (10.3) | ||
| Inattention score | 17.85 (5.47) | 18.2 (5.4) | 16.6 (5.4) | <.001 | 17.4 (5.8) | 18 (5.3) | >.1 | 17.9 (5.4) | 17.8 (5.5) | > .1 |
| Hyperactive score | 8.76 (6.0) | 12.5 (7.1) | 10.1 (6.4) | <.001 | 11.4 (7.2) | 12.3 (6.9) | >.1 | 13.8 (6.8) | 9.8 (6.7) | <.001 |
| T2 ADHD-RS-IV (SD) | 23.33 (14.19) | 24.2 (14.5) | 20 (12.6) | <.001 | 23.6 (15.7) | 23.2 (13.4) | 24.3 (14.1) | 22 (14.2) | ||
| Inattention score | 14.60 (8.7) | 15.2 (8.9) | 12.3 (7.6) | <.001 | 14.8 (9.9) | 14.5 (8.2) | >.1 | 15.1 (8.6) | 14 (8.7) | > .1 |
| Hyperactive score | 8.76 (6.0) | 9 (6.1) | 7.7 (5.6) | <.001 | 8.9 (6.5) | 8.7 (5.8) | >.1 | 9.2 (6) | 8 .1 (6) | .049 |
| T1-T2 ADHD-RS-IV | <.001 | <.001 | ||||||||
| SNAP-IV | ||||||||||
| T1 ODD score | 10.08 (4.47) | 10.1 (4.5) | 8.7 (4.7) | <.001 | 9.3 (4.7) | 10.1 (4.5) | >.1 | 9.9 (4.7) | 9.9 (4.7) | > .1 |
| T2 ODD score | 6.36 (5.0) | 6.7 (5) | 4.8 (4.5 | <.001 | 6.2 (4.9) | 6.4 (4.9) | >.1 | 6.7 (5) | 5.9 (5) | > .1 |
| T1-T2 ODD score | <.001 | <.001 | <.001 | |||||||
| CGI-S | ||||||||||
| T1 CGI-S | 3.85 (0.77) | 3.9 (0.8) | 3.7 (0.8) | .09 | 3.9 (0.7) | 3.8 (0.8) | >.1 | 3.8 (0.8) | 3.9 (0.8) | >.1 |
| T2 CGI-S | 2.71 (0.94) | 2.7 (0.9) | 2.6 (0.9) | .06 | 2.7 (0.9) | 2.7 (0.9) | >.1 | 2.8 (0.9) | 2.8 (0.9) | .009 |
| T1-T2 CGI-S | <.001 | <.001 | <.001 | |||||||
Note: ADHD = Attention-deficit/hyperactivity disorder. ADHD subtype presentation: IA (inattentive); C (Combined). ADHD-RS-IV.es: ADHD rating scale-IV (Spanish version). ODD: oppositional defiant disorder CGI-S: Clinical Global Impressions Severity Scale. T1: baseline; T2: end point-last follow-up visit. p<0.005: statistically significant *Children (<11.9y), Adolescents (12-18y)