FIGURE 4.

Extracellular matrix-based matrices and drug interaction-based delivery systems. (A) Growth factor retention in fibrin matrices with laminin-mimetic peptides (α2PI1–8-LAMA33043–3067 or α2PI1–8-LAMA53417–3436) or without peptide (**p < 0.01) (Ishihara et al., 2018). Copyright 2018. Reproduced with permission from Springer Nature. (B) The scheme of study design. Antimicrobial activity of LL37 and with collagen-binding domains (cCBD-LL37 or fCBD-LL37) on collagen scaffold after 12 h and 14 days (*p < 0.01, **p < 0.001, ⁺p < 0.05) (Lozeau et al., 2017). Copyright 2017. Reproduced with permission from Elsevier Inc.