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. 2020 Feb 18;14:45. doi: 10.3389/fnins.2020.00045

FIGURE 4.

FIGURE 4

The efficiency of Src inhibitor PP2 was confirmed in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice. (A) The experimental arrangement. (B–D) The protein level of p-Src and Src in SNpc of MPTP-treated mice was analyzed by western blot with anti-p-Src and anti-Src antibodies. Data are expressed as means ± SEM. n = 4. #P < 0.05 vs. control group,***P < 0.001 vs. lipopolysaccharide (LPS) group. (E) The brown stain represented p-Src-immunoreactive cells in SNpc (scale bar: top, 600 μm; bottom, 25 μm). (F) The number of p-Src-positive cells per 100 cells in SNpc was counted and provided in a histogram. Data are expressed as means ± SEM. n = 4. #P < 0.05 and ##P < 0.01 vs. control group, **P < 0.01 and ***P < 0.001 vs. MPTP group.