Appendix 1. Detailed search strategy in PubMed.
| Search | Query | Items Found | Facet |
|---|---|---|---|
| 1 | Search prostate neoplasms OR neoplasms,prostate OR neoplasm,prostate OR prostate neoplasm OR neoplasms,prostatic OR neoplasm,prostatic OR prostatic neoplasm OR prostate cancer OR cancer,prostate OR cancers, prostate OR prostate cancers OR cancer of the prostate OR prostatic cancer OR cancer, prostatic OR cancers,prostatic OR prostatic cancers OR cancer of prostate. | 153098 | Disease |
| 2 | Search prostate cancer. | 149845 | |
| 3 | Search (#1 or #2). | 154135 | |
| 4 | Search (Nilutamide[Supplementary Concept]) OR Nilutamide. | 293 | Intervention |
| 5 | Search ((((((5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)- 2,4 imidazolidinedione) OR Nilandron) OR Nilutamide) OR RU 23908-10) OR Anandron) OR RU 23908) OR RU-23908. | 311 | |
| 6 | Search (#4 OR #5). | 24046 | |
| 7 | Search (#3 AND #6). | 1092 | D+I |
| 8 | Search (#3 and #6) Filters: Humans. | 244 | Filters |