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. 2019 Oct;26(10):751–757. doi: 10.2174/0929866526666190503105343

Figure 1.

Figure 1

Down-regulation of NMAAP1 promotes macrophage shift from M1 to M2. (A) Gene and protein expression of NMAAP1 in ConNM/RAW264.7 and SiNM/RAW264.7 cells was detected by qRT-PCR and Western-blotting. (B) Genes expression in ConNM/RAW264.7 and SiNM/RAW264.7 cells was detected by qRT-PCR. (C) ELISA was used to detect the secretion of TNF-α, IL-1, IL-12p40, IL-10 and TGF-β by ConNM/RAW264.7 and SiNM/RAW264.7 cells. (Note: ConNM/RAW264.7: siRNA control sequence transfected cells; SiNM/RAW264.7: NMAAP1 siRNA sequence transfected cells). * P < 0.05, ** P < 0.01, *** P < 0.001.