Table 2. Clinical features and pathogens defining the presence of a fungal OI.

Fungi	Clinical Condition
Candida spp. [13, 14, 16, 18]	Severe oropharyngeal candidiasis, esophagitis, candidiasis of trachea and bronchi. Pulmonary candidiasis secondary to tracheobronchial infection is not considered as possible outside some specific neonatal conditions. Invasive candidiasis (end-organ disease, including hematogenous pneumonia).
Aspergillus spp. [13, 14, 16, 19, 25]	Invasive disease only.
Pneumocystis jirovecii [13, 14, 16, 19, 25]	Pneumonia or disseminated infections.
Cryptococcus spp. [13, 14, 16, 23, 26, 27]	Cryptococcosis, extrapulmonary: fungemia, meningitis, osteoarticular, disseminated cutaneous.
Coccidioides immitis [13, 14, 16, 26]	Coccidioidomycosis, disseminated or extrapulmonary.
Histoplasma capsultum [13, 14, 16, 26]	Histoplasmosis, disseminated or extrapulmonary.
Other fungi: [13, 14, 16] Mucormycosis (zygomycosis) (Rhizopus, Mucor and Lichtheimia), Scedosporium/Pseudallescheria boydii, Fusarium, Thalaromyces spp (previously Penicillium marneffei) Geotrichum spp., Saprochaete spp., Magnusiomyces spp.	Invasive disease.