Table 1.
Patient and procedural characteristics
| Type of anticoagulant | ||
|---|---|---|
|
Warfarin n = 21 |
DOAC n = 86 |
|
| Patient characteristics | ||
| Age, median (LQ; UQ) | 71 (62; 79) | 73 (67; 78) |
| BMI (kg/m2), median (LQ; UQ) | 28.8 (25.7; 31.6) | 30.0 (26.2; 34.1) |
| Systolic blood pressure (mm Hg), median (LQ; UQ) | 123 (118; 148) | 133 (121; 146) |
| Cockcroft‐Gault CrCl (mL/min), median (LQ; UQ) | 78 (47; 121) | 76 (54; 102) |
| Female gender, n (%) | 3 (14) | 32 (37) |
| Smoker, n (%) | 1 (5) | 7 (8) |
| Concurrent antiplatelet therapy, n (%) | 0 | 9 (11) |
| Periodontitis as extraction indication,a n (%) | 17 (81) | 61 (71) |
| Oral anticoagulant indication, n (%) | ||
| AF | 13 (62) | 69 (80) |
| VTE | 5 (24) | 13 (15) |
| AF + VTE | 2 (10) | 2 (2) |
| Other | 1 (5) | 2 (2) |
| DOAC dosing regimen,b n (%) | Apixaban | |
| Higher dose | 22 (54) | |
| Lower dose | 16 (39) | |
| Other | 3 (7) | |
| Dabigatran | ||
| 6 (40) | ||
| 8 (53) | ||
| 1 (7) | ||
| Rivaroxaban | ||
| 25 (83) | ||
| 4 (13) | ||
| 1 (3) | ||
| Procedural characteristics | ||
| Number of teeth extracted, median (LQ; UQ) | 2 (1; 3) | 1 (1; 2) |
| Extraction duration (mins), median (LQ; UQ) | 22 (11; 37) | 17 (11; 27) |
| Mouthwash use prior to dental extraction, n (%) | 6 (29) | 29/85 (34) |
| Preextraction antibiotic use, n (%) | 3 (14) | 10 (12) |
| Extraction of posterior teeth compared to anterior teeth only, n (%) | 16 (76) | 60 (70) |
| Gingival bleeding on probing,c n (%) | 11/18 (61) | 33/66 (50) |
| Surgical extraction compared to simple extraction, n (%) | 2 (10) | 15 (17) |
| Achievement of primary closure, n (%) | 11 (52) | 20 (23) |
Abbreviations: AF, atrial fibrillation; BMI, body mass index; CrCl, creatinine clearance; LQ, lower quartile; NA, not applicable; UQ, upper quartile; VTE, venous thromboembolism.
a
Nonperiodontitis indications include deep caries and cracked tooth.
b
Higher dose = apixaban 5 mg twice a day, dabigatran 150 mg twice a day, rivaroxaban 20 mg daily. Lower dose = apixaban 2.5 mg twice a day, dabigatran 110 mg twice a day, rivaroxaban 15 mg daily. Other (dosing outside the approved dosing regimen) = daily dosing of apixaban/dabigatran, alternate‐day rivaroxaban.
c
Bleeding on probing is an indication of active gingival inflammation.