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. 2019 Dec 26;4(2):183–192. doi: 10.1002/rth2.12290

Figure 3.

Figure 3

Overview of the Highlow study (http://www.highlowstudy.org; NCT01828697, clinicaltrials.gov). (A) Study flowchart from randomization to follow up; (B and C) Eligibility criteria, primary efficacy outcome, and primary safety outcomes