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. 2020 Jan 9;43(3):783–794. doi: 10.3892/or.2020.7458

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Copyright: © Lu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — PPM1D promotes the cell migration and invasiveness of thyroid cancer cells in vitro. (A) Cell migration was quantified by wound healing assay. Cells were imaged immediately (0 h) and 48 h after scratches were created to assess the percentage of the wound-healed area. Representative images at different time-points are provided on the left (scale bar, 100 µm) and quantitative measurements are displayed on the right. (B and C) Cell invasion was assessed using a Transwell invasion assay. (B) Representative imagines (scale bar, 100 µm) and (C) Quantitative measurements. Values are expressed as the mean ± SEM of three independent experiments. P-values were determined using ANOVA test followed by Tukey's test. ***P<0.001. PPM1D, protein phosphatase, Mg²⁺/Mn²⁺ dependent, 1D.