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. 2020 Feb 24;21:182. doi: 10.1186/s12864-020-6569-1

Table 3.

The performance evaluation on HG38 and the diploid sequence of NA12878. The performance on SNV and Indel detection implies that the diploid genome sequence and the reference variants are not fully compatible

Dataset Method SNV Indel Run time (min) Memory usage (GB)
Precision Recall Precision Recall
NA12878 (Diploid) GSAlign 0.832 0.969 0.759 0.767 5 14
Minimap2 0.830 0.970 0.754 0.768 65 23
MUMmer4 0.752 0.946 0.711 0.749 3898 57
LAST 0.832 0.969 0.760 0.764 1305 28